The ex vivo pharmacology of HIV-1 antiretrovirals differs between macaques and humans
Summary: Non-human primates (NHP) are widely used for the pre-clinical assessment of antiretrovirals (ARVs) for HIV treatment and prevention.However, the utility of these models is questionable given the differences in ARV pharmacology between humans and macaques.Here, TEA TREE SOAP we report a model based on ex vivo ARV exposure and the challenge